This additive modifies the microbiota

A very common additive, E415, which serves as a thickener, could be digested by certain bacteria in our microbiota. The health implications are still unknown at this time.

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[EN VIDÉO] The intestinal microbiota, a valuable ally for our health
There are different microbiota in the body: that of the skin, the mouth, the vagina… But the most important is the intestinal microbiota. Scientists have known about its potential for a long time, but the development of new techniques allows further research to describe the nature of host-microbiota interactions, those of microorganisms with each other, and their impact on health.

Xanthan gum, or E415, is an additive present in many industrial foods where it serves as a thickener. It is a long branched chain made up of four sugars: glucose, mannosemeAcide et base conjuguée
À tout acide correspond une base conjuguée…” data-image=”” data-url=”” data-more=”Lire la suite”>acid
glucuronique yl’Sa base conjuguée est l’anion pyruvate CH3-CO-COO-, une molécule biologique impliquée dans des voies métaboliques majeures.” data-image=”” data-url=”” data-more=”Lire la définition”>pyruvic acid. It is considered non-hazardous to health because it is not metabolized by the human body. However, a recent study published in microbiology of nature indicates that xanthan gum has an effect, not on our cells, but on the bacteria of our gut microbiota. This additive has only been present in the so-called Western diet – where ultra-processed foods have an important place – for about fifty years. A blink of an eye in terms of evolution, but gut bacteria have evolved enzymes able to break down xanthan gum and digest it.

An additive digested by intestinal bacteria.

One of bacteria in question belongs to the family of Ruminococcaceae. Its “xantanophage” activity was brought to light by two researchers from the University of Michigan in the United States during a series of experiments carried out on human samples, Classification de la souris de laboratoire
La souris de laboratoire est un eucaryote, mammifère de l’ordre des Rongeurs et de la famille des Muridés.
Caractéristiques de la souris de…” data-image=”” data-url=”” data-more=”Lire la suite”>Laboratory mouse
then bioinformatic analysis. « Bacteria that can digest xanthan gum have been isolated from the gut microbiota of a surprisingly large number of people in industrialized countries », explains Sabina Leanti La Rosa, one of the researchers who participated in the project.

a second bacterium intestinal bacteria, capable of digesting the additive was isolated from a single sample. The latter was able to digest the remains of xanthan gum after the first bacteria attacked the La liaison dite covalente simple…” data-image=”” data-url=”” data-more=”Lire la suite”>molecule whole. Does this affect our health? It still seems too early to tell. According to Sabina Leanti La Rosa: “ Based on this study, we cannot conclude if and how xanthan gum affects our health. But we can say that this additive affects the intestinal microbiota of people who ingest it through food. »

Long-licensed, xanthan gum has been re-evaluated by theEuropean Food Safety Authority (L’AESA est une source indépendante de conseils scientifiques et de communication dans le domaine des risques…” data-url=”” data-more=”Lire la suite”>EFSA) in 2017. The article concludes that xanthan gum is not dangerous to health, although it can produce laxative effects in some people. Already at that time it was mentioned that the additive ” could be partially fermented during its passage through the Fonction du côlon
Aussi appelé gros intestin, le côlon fait suite à l’intestin grêle et forme la dernière partie du système digestif. Il est constitué de plusieurs parties :
le cæcum (d’où part l’appendice vermiforme) ;le côlon ascendant (droit) ;le…” data-image=”” data-url=”” data-more=”Lire la suite”>large intestine
by the action of the intestinal microbiota
“. The study conducted at the University of Michigan confirms this. E415 is not the first additive suspected of altering the Rôle des bactéries intestinales
Des millions de bactéries vivent dans notre intestin sans engendrer de pathologie. Elles sont même essentielles au bon fonctionnement…” data-image=”” data-url=”” data-more=”Lire la suite”>gut flora
; E171 and E466 could be involved in inflammatory problems in the intestine.

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